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Panfungal Detection

Fungus (1-3)-β-D-Glucan Assay

Catalogue Number:DNK-1401-1

Specifications:96 tests

Specimen:Serum

Reaction Time:40 minutes

User Manual Product Catalogue

Description
(1-3)-β-D-glucan is widely present in the fungal cell wall and acts as a specific biomarker for fungal infection. The glucan specifically binds to factor G in the Main Reagent, activating its serine protease zymogen. The cascade of reactions changes the absorbance of the substrate and quantifies the (1-3)-β-D-glucan concentration.

Advantage
1.Microplate reader detection at 405nm using kinetic chromogenic method: Matches with international standard.
2.High throughput and rapid detection: It takes only 40 minutes to complete diagnosis for 90 sets of samples
3.Breakable microplate strips: Flexible and easy to use
4.Samples with background color (such as jaundice, hemolysis etc.) have little effect on the diagnosis
5.Small amount of patient sample needed: Only 20μl of serum for each test
6.Safe and convenient experimental procedures: Reduces rate of contamination and workload

Test Procedure

Features
High-Risk Population
Specimen            Serum
Specification         96 tests / kit
Detection Range      37.5-600pg/m
Percent Recovery     75%-125%
Endotoxin Sheilding    1.0 EU/mL
Intra-assay CV         ≤10%
Inter-assay CV         ≤12%
Neutropenic(Neutrophil conc. <0.5x10 9/L)
    Bone marrow and solid organ transplantation
    Anti-tumor agent and immunosuppressant
Non-neutropenic
    Long-term hormone therapy 
    Long-term use of broad-spectrum antibiotics                      
    Intubation and other invasive treatments

    HIV infection
    Chronic obstructive pulmonary disease
    ICU inpatient