Cryptococcus neoformansis an opportunistic fungal pathogen that cancause cryptococcal meningitislung and skin infections,in immunocompromisedindividuals. Cryptococcosis, caused by Cryptococcus spp., is one of themost common opportunistic infections among humanimmunodeﬁciency virus (HIV)infectedindividuals. Globally, almost1 million new cases of cryptococcal meningitis are observedper year, with >600,000deaths.
This kit uses a specific monoclonal antibody againstthe Cryptococcus neoformansGXM and providesaneffective testto monitor the susceptible population.
1.Microplate reader detection at 405nm using kinetic chromogenic method: Matches with international standard.
2.High throughput and rapid detection: It takes only 40 minutes to complete diagnosis for 90 sets of samples
(1-3)-β-D-glucan is widely present in the fungal cell wall and acts as a specific biomarker for fungal infection. The glucan specifically binds to factor G in the Main Reagent, activating its serine protease zymogen. The cascade of reactions changes the absorbance of the substrate and quantifies the (1-3)-β-D-glucan concentration.